Clinical References
1. Chen Y et al: Mesenchymal stem cells: a promising candidate in regenerative medicine. Int J Biochem Cell Biol, 2008;40(5):815-20
2. Maumus M, Jorgensen C, Noël D: Mesenchymal stem cells in regenerative medicine applied to rheumatic diseases: role of secretome and exosomes. Biochimie, 2013;95(12):2229-34
3. Zuk PA et al: Human adipose tissue is a source of multipotent stem cells. Molecular Biology of the Cell, 2002;13(12):4279-95
4. Djouad F et al: Mesenchymal stem cells: innovative therapeutic tools for rheumatic diseases. Nat Rev Rheuatol, 2009;5:392-9
5. Kilroy GE et al: Cytokine profile of human adipose-derived stem cells: expression of angiogenic, hematopoietic, and pro-inflammatory factors. J Cell Physiol, 2007;212(3);702-9
6. Conese M et al: Paracrine effects and heterogeneity of marrow-derived stem/progenitor cells: relevance for the treatment of respiratory diseases. Cells Tissues Organs, 2013;197(6):445-73
7. Pers YM et al: Adipose Mesenchymal Stromal Cell-Based Therapy for Severe Osteoarthritis of the Knee: A Phase I Dose-Escalation Trial. 2016;5(7):847-56
8. Koh YG et al: Comparative outcomes of open-wedge high tibial osteotomy with platelet-rich plasma alone or in combination with mesenchymal stem cell treatment: a prospective study. Arthroscopy, 2014;30(11):1453-60
9. Pak J et al: Cartilage Regeneration in Human with Adipose Tissue-Derived Stem Cells: Current Status in Clinical Implications. BioMed Research International, 2016
10. Im GI: Regeneration of articular cartilage using adipose stem cells. Journal of Biomedical Materials Research, 2016;104(7):1830-44
11. Xu FT et al: Effect of activated autologous platelet-rich plasma on proliferation and osteogenic differentiation of human adipose-derived stem cells in vitro Am J Transl Res, 2015;7(2):257-70
12. Shen J et al: Autologous platelet-rich plasma promotes proliferation and chondrogenic differentiation of adipose-derived stem cells. Molecular Medicine Reports, 2015;11(2):1298-303
13. Loibl M et al: The effect of leukocyte-reduced platelet-rich plasma on the proliferation of autologous adipose-tissue derived mesenchymal stem cells. Clin Hemorheol Microcirc, 2016;61(4):599-614
14. Van Pham P et al: Activated platelet-rich plasma improves adipose-derived stem cell transplantation efficiency in injured articular cartilage. Stem Cell Research & Therapy, 2013;4(4):91
15. Stessuk T et al: Platelet-rich plasma (PRP) and adipose-derived mesenchymal stem cells: stimulatory effects on proliferation and migration of fibroblasts and keratinocytes in vitro. Arch Dermatol Res, 2016;308(7):511-20
16. Tang XB et al: Effect of autologous platelet-rich plasma on the chondrogenic differentiation of rabbit adipose-derived stem cells in vitro. Experimental and Therapeutic Medicine, 2015;10(2):477-83
17. Mazzocca A et al: Platelet-rich plasma differs according to preparation method and human variability. Journal of Bone & Joint surgery. 2012;94(4):308-16
18. Borzini P, Mazzucco L: Tissue regeneration and in loco administration of platelet derivates: clinical outcomes, heterogeneous products, and heterogeneity of effector Mechanisms. Transfusion. 2005;45(11):1759-67
19. Edwards D et al: Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor. The EMBO Journal. 1987;6(7):1899-904
20. Lynch SE et al: role of platelet-derived growth factor in wound healing: synergistic effects with other growth factors. Proc. Natl. Acad. Sci. USA. 1987;84(21):7696-700
21. Mazzocca A et al: The positive effects of different platelet-rich plasma methods on human muscle, bone, and tendon cells. The American Journal of Sports Medicine. 2012; 40(8):1742-49
22. Cho J W et al: Platelet-rich plasma induces increased expression of G1 cell cycle regulators, type I collagen, and matrix metalloproteinase-1 in human skin fibroblasts. International Journal of Molecular Medicine. 2012;29(1):32-6
23. Andia I et al: Basic Science: Molecular and Biological Aspects of Platelet-Rich Plasma Therapies. Operative Techniques in Orthopaedics. 2012;22(1):3-9
24. Van Dongen JA et al: The fractionation of adipose tissue procedure to obtain stromal vascular fractions for regenerative purposes. Wound Repair and Regeneration, 2016;24(6):994-1003
25. Kasir R, Vernekar VN, Laurencin CT: Regenerative Engineering of Cartilage using Adipose-Derived Stem Cells. Regen Eng Transl Med, 2015;1(1):42-49
26. Yoshimura K et al: Characterization of freshly isolated and cultured cells derived from the fatty and fluid portions of liposuction aspirates. Journal of Cellular Physiology. 2006;208(1):64-76
27. Shukla et al: Adipose-derived stem cells in radiotherapy injury: a new frontier. Frontiers in Surgery, 2015;2(1):1-12
28. Pers et al: Adipose derived stem cells for regenerative therapy in osteoarticular diseases. Horm Mol Biol Clini Invest, 2016;28(3):113-120
29. Hoogduijn et al: Human heart, spleen, and perirenal fat-derived mesenchymal stem cells have immunomodulatory capacities. Stem Cells Dev 2007;16:597-604
30. Puissant et al: Immunomodulatory effect of human adipose tissue-derived adult stem cells: comparison with bone marrow mesenchymal stem cells. Br J Haematol 2005;129:118-29
31. Wolbank et al: Dose-dependent immunomodulatory effect of human stem cells from amniotic membrane: a comparison with human mesenchymal stem cells from adipose tissue. Tissue Eng 2007;13:1173-83.
32. Yanez et al: Adipose tissue-derived mesenchymal stem cells have in vivo immunosuppressive properties applicable for the control of the graft-versus-host disease. Stem Cells 2006;24:2582-91.
33. Luz-Crawford et al: Mesenchymal stem cell derived IL1RA promotes macrophage polarization and inhibits B cell differentiation. Stem Cells 2016;34:483-92.
34. Koh et al: Adipose-Derived Mesenchymal Stem Cells With Microfracture versus Microfracture alone: 2-Year Follow-up of a Prospective Randomized Trial. Arthroscopy, 2016;32(1):97-109
35. Michalek et al: Autologous adipose tissue-derived stromal vascular fraction cells application in patients with osteoarthritis. Cell Transplant, 2015
36. Nguyen et al: Comparative Clinical Observation of Arthroscopic Microfracture in the Presence and Absence of a Stromal Vascular Fraction Injection for Osteoarthritis. Stem Cells Trans Med, 2016;5:1-9
37. Konrad Słynarski et al: Treatment of Osteoarthritis: Adipose Derived Stem Cell and PRP Therapy. Sportärztezeitung. 2017;3:14-18